Toxicology is a branch of science that deals with poisons. A poison is any substance that causes a harmful effect when administered, either by accident or design, to a living organism. Toxicology also includes the study of harmful effects caused by physical phenomena, such as radiation of various kinds and noise. Toxicity itself can rarely be defined as a single molecular event but is, rather, a cascade of events starting with exposure, proceeding through distribution and metabolism, and ending with interaction with cellular macromolecules (usually DNA or protein) and the expression of a toxic end point. This sequence may be mitigated by excretion and repair. It is to the complications, and to the science behind them and their resolution, that this course is all about, particularly to the how and why certain substances cause disruptions in biological systems that result in toxic effects. The course also studies the metabolic and physiological factors affecting chemotherapeutic agents and the theories of the mechanism of drug action.
- Teacher: OLUBANKE OLUJOKE OGUNLANA
This course provides information on the developmental history of biochemistry leading to the emergence of biochemistry as vital field of science. It also introduces students to the basic technique employed in the field, the relevance of the field to national development, and employment opportunities available to biochemist.